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Entos to develop Fusogenix DNA vaccine to prevent Covid-19 infections (Pharmaceutical Business Review (PBR)) - Mar 19, 2020 - "Entos Pharmaceuticals has unveiled plans to develop a Fusogenix DNA vaccine for the prevention of COVID-19 infections....Upon completion of the development of the Fusogenix DNA vaccine formulation, the company will begin preclinical testing for safety and efficiency....The company will also work...for the advancement of novel Fusogenix vaccine to human clinical trials."Stabilitech's Covid-19 vaccine for oral administration as a revolutionary thermally stable capsule (PRNewswire) - Mar 19, 2020 - "Stabilitech BioPharma...announced the development of a prototype COVID-19 starting viral stock which it intends to manufacture and administer orally in the form of patented capsules....Once approved by regulatory authorities, the Stabilitech vaccine will shake up the market thanks to its safe and effective self-administered capsules....The Company is currently in talks with a range of investors to finance its assets under development and benefits from the EIS Advance Assurance guarantee from the British tax authorities (HMRC)."leronlimab (PRO 140) / CytoDyn, Vyera PharmaU.S. Food and Drug Administration (FDA) grants emergency IND for two coronavirus patients treated in New York with CytoDyn’s leronlimab (GlobeNewswire) - Mar 19, 2020 - “CytoDyn Inc…announced today that two coronavirus patients were treated with the Company’s investigational new drug, leronlimab. The treatment was administered at a leading medical center in the New York City area under an emergency Investigational New Drug (IND) recently granted by the U.S. Food and Drug Administration (FDA). Leronlimab is intended to serve as a therapy for patients who experience respiratory illness as a result of contracting the Coronavirus Disease 2019 (COVID-19).”INDMateon partners with Meridian IT to fast track drug manufacturing using artificial intelligence for coronaviruses, including COVID-19 (GlobeNewswire, Mateon Therapeutics) - Mar 19, 2020 - "Mateon intends to leverage on the AI machine vision technology used in the retail use cases to pharmaceutical manufacturing, especially with our lead product OT-101, which we are testing for coronaviruses, including the current COVID-19."Japanese researchers to take a look at blood thinner for coronavirus treatment (Gotech Daily) - Mar 19, 2020 - "A blood thinner...has been recognized as a probable treatment for COVID-19 individuals, with clinical trials in Japan possibly established to begin within a thirty day period, scientists at the College of Tokyo mentioned Wednesday....The drug, recognised by the scientific name nafamostat....The team located the drug’s probable potential by an experiment simulating the coronavirus’s an infection of human cells."ifenprodil (NP-120) / Algernon PharmaAlgernon to support planned phase 2 trial of ifenprodil for coronavirus (GlobeNewswire, Algernon Pharmaceuticals) - Mar 19, 2020 - "Algernon Pharmaceuticals...is pleased to announce that Novotech...has identified physicians in South Korea who have agreed to conduct an investigator initiated phase 2 clinical trial of Ifenprodil for coronavirus patients....Novotech was asked to advise on the most efficient regulatory approach to initiating a phase 2 clinical trial for Ifenprodil for COVID-19....The study approval process may be expedited due to the current global health crisis."The updates on Covid-19 in Korea as of 19 March (KCDC) - Mar 19, 2020 - "The KNIH is currently conducting a study of clinical epidemiology and immunology of COVID-19 patients and hopes that its findings will inform infection prevention policies." "Stabilitech's COVID-19 vaccine intended to be delivered in a disruptive thermally stable oral capsule (PRNewswire) - Mar 19, 2020 - "Stabilitech BioPharma Ltd...this morning announces the completion of its COVID-19 Master Viral Seedstock, which it now intends to have manufactured and formulated into its patent protected capsule for oral vaccine delivery. Once approved by the regulatory authorities, Stabilitech will disrupt the vaccine market by producing safe, efficacious, self-administered vaccine capsules that are inexpensive to produce, developed in weeks, thermally stable and can be posted direct to consumer."Coronavirus Vaccine / EpiVax, GenerexGenerex Biotechnology provides guidance on the safety of Ii-key peptide vaccines for the development of effective solutions to the SARS-CoV-2 coronavirus pandemic (GlobeNewswire, Generex Biotechnology Corporation) - Mar 19, 2020 - "Generex Biotechnology Corporation...today provided guidance on their work to develop a peptide vaccine against the new coronavirus SARS-CoV-2 using the company’s proprietary and patented Ii-Key immune system activation technology. This guidance is designed to assist third party groups and government agencies in their evaluation of potential vaccines against this pandemic SARS-CoV-2 virus. The patented NuGenerex Immuno-Oncology (Formerly Antigen Express) Ii-Key technology uses synthetic peptides that mimic essential protein regions from a virus that are chemically linked to the 4-amino acid Ii-Key to ensure robust immune system activation."Phathom reports fourth quarter and full year 2019 financial results and provides clinical trial status and business updates (GlobeNewswire, Phathom Pharmaceuticals) - Mar 19, 2020 - "Due to the COVID-19 global pandemic, the Company is temporarily pausing new patient randomization in its PHALCON-EE and PHALCON-HP clinical trials....The temporary pause on new patient randomization aligns with the American Society for Gastrointestinal Endoscopy’s guidance on limiting endoscopies, which are required in both clinical trials, due to the COVID-19 pandemic and supports various governments’ restrictions on travel."
