Discover
remdesivir / Generic mfg.Armenian Health Minister Approves Use of Remdesivir to Treat Severe Covid-19 Cases (Hetq) - Aug 12, 2020 - "Armenia’s Minister of Health Arsen Torosyan...approved use of the drug in the medical centers that have been refitted for Covid-19 treatment. Physicians must prescribe (sic) the drug for their patients."NVX-CoV2373 / NovavaxNovavax and UK Government Announce Collaboration and Purchase Agreement for Novavax’ COVID-19 Vaccine Candidate (GlobeNewswire) - Aug 14, 2020 - "Novavax, Inc....today announced it has signed a Heads of Terms (Term Sheet) with the Government of the United Kingdom (UK) for the purchase of 60 million doses...and a Phase 3 clinical trial to assess the efficacy of the vaccine in the UK population.....Novavax will also expand its collaboration with FUJIFILM Diosynth Biotechnologies....The FUJIFILM Diosynth Biotechnologies site in the UK is expected to produce up to 180 million doses annually....The trial is expected to begin in the third quarter of this year..."remdesivir / Generic mfg.; favipiravir / Generic mfg.Egypt approves requests from 61 companies to produce Favipiravir (Egypt Independent) - Aug 11, 2020 - "The Egyptian Drug Authority (EDA) announced Tuesday that it has granted its initial approval to 61 national pharmaceutical companies to begin production for the antiviral drug Favipiravir....EDA explained that these companies have been given the clear to begin all administrative and technical steps towards registering Favipiravir....The authority also approved the applications submitted by 27 national pharmaceutical companies to finalize registration of the Remdesivir drug....One national company obtained EDA documents to start manufacturing Remdesivir..."remdesivir / Generic mfg.Gilead Submits New Drug Application to U.S. Food and Drug Administration for Veklury (Remdesivir) for the Treatment of COVID-19 (Businesswire) - Aug 10, 2020 - "Gilead Sciences...announced today that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for Veklury® (remdesivir), an investigational antiviral for the treatment of patients with COVID-19....The filing is supported by data from two randomized, open-label, multi-center Phase 3 clinical studies of Veklury conducted by Gilead and the Phase 3 randomized, placebo-controlled study of Veklury conducted by the National Institute of Allergy and Infectious Diseases (NIAID)."remdesivir / Generic mfg.; Olumiant (baricitinib) / Incyte, Eli Lilly, University of ColoradoUNMC to start third phase of federal COVID-19 drug trial (Omaha World-Herald) - Aug 9, 2020 - "The Omaha-based arm of a new phase of an international drug trial testing medications for people hospitalized with COVID-19 is expected to begin this week....The third phase of the trial...will pair the antiviral drug remdesivir with a type of interferon used to treat multiple sclerosis and some kinds of hepatitis....Researchers then paired remdesivir with an anti-inflammatory drug, Kalil said. That portion of the trial closed a month ago, and researchers hope to have the results by the end of the month."favipiravir / Generic mfg.FDA Clears Appili Therapeutics to Expand its Phase 2 Clinical Trial of Favipiravir for the Potential Prevention of COVID-19 at U.S. Long-Term Care Facilities (Businesswire) - Aug 10, 2020 - "Appili Therapeutics...today announced that the U.S. Food and Drug Administration (FDA) has granted the Company clearance to proceed after Appili’s filing of an investigational new drug (IND) application for broad-spectrum antiviral favipiravir. Appili is expanding its Phase 2 clinical trial into the U.S. to evaluate the safety and efficacy of favipiravir tablets...Appili intends to enroll up to 760 participants in this Phase 2 clinical trial across both the U.S. and in Canada."Gam-COVID-Vac Lyo / Gamaleya Research InstituteCoronavirus: Putin says vaccine has been approved for use (BBC) - Aug 11, 2020 - "Russian President Vladimir Putin has said a locally developed vaccine for Covid-19 has been given regulatory approval after less than two months of testing on humans. Mr Putin said the vaccine had passed all the required checks, adding that his daughter had already been given it. Officials have said they plan to start mass vaccination in October....WHO said it had been in talks with Russian authorities about undertaking a review of the vaccine, which has been named Sputnik-V....Vaccine's approval by Russian regulators comes before the completion of a larger study involving thousands of people, known as a phase-three trial."remdesivir / Generic mfg.Zydus Cadila launches COVID-19 drug Remdesivir in India (Outlookindia.com) - Aug 13, 2020 - "Drug firm Zydus Cadila on Thursday said it has launched Remdesivir under the brand name Remdac, used to treat patients suffering from severe symptoms of COVID-19, in the Indian market. Priced at Rs 2,800 per 100 mg vial, Remdac is the most economical Remdesivir brand in India, Zydus Cadila said in a regulatory filing."AZD1222 / Oxford Biomedica, Emergent Biosolutions, Jenner Institute, Vaccitech, AstraZeneca, University of OxfordArgentina, Mexico to produce AstraZeneca COVID-19 vaccine (Reuters) - Aug 13, 2020 - "Argentina and Mexico will produce the AstraZeneca COVID-19 vaccine for most of Latin America, Argentine President Alberto Fernandez said on Wednesday...An agreement signed between British pharmaceutical company AstraZeneca and the biotechnology company mAbxience of the INSUD Group includes transfer of technology to initially produce 150 million doses of the vaccine to supply all of Latin America with the exception of Brazil, the Argentine government said....AstraZeneca...signed a deal with the foundation of Mexican billionaire Carlos Slim for production of the vaccine, which is expected to be delivered in the first half of 2021..."Vyrologix (leronlimab) / CytoDyn, Vyera PharmaCytoDyn Announces Clinically Significant Top-line Results from its Phase 2 Trial in Mild-to-Moderate COVID-19 Patients (GlobeNewswire) - Aug 11, 2020 - P2, N=75; NCT04343651; Sponsor: CytoDyn Inc; "At Day 3, more subjects treated with leronlimab reported improvement in total clinical symptom score compared to the placebo group (90% on leronlimab arm vs. 71% on placebo)....In all treated patients, at the End of Treatment (or Day 14), patients in the leronlimab group were more than twice as likely to experience a beneficial improvement in scores compared to patients in the placebo group (50% vs 20%; p=0.0223). Similar, statistically significant, results were observed at Day 3 and Day 14 in the analysis of per protocol population (premdesivir / Generic mfg.Iran eyes regional market for homegrown remdesivir (Tehran Times) - Aug 15, 2020 - "The Iranian remdesivir medicine has been formulated and produced to cure COVID-19 patients and is currently undergoing legal registration with the Food and Drug Administration to enter the market by the next two weeks, IRNA quoted Hossein Vatanpour as saying on Saturday."CERC-002 / Kyowa Hakko Kirin, Sanofi, CerecorCerecor Announces Peer-Reviewed Publication Highlighting the Role of the Inflammatory Cytokine, LIGHT, in COVID-19 ARDS (GlobeNewswire) - Aug 13, 2020 - P=NA, N=47; "Cerecor Inc....today announced the publication of a peer-reviewed paper demonstrating significantly elevated free LIGHT levels in the serum of hospitalized patients with severe COVID-19 infection. The publication...highlights the potential role of the inflammatory cytokine, LIGHT in the development of COVID-19 ARDS....Publication supports its clinical program evaluating CERC-002....'This study is now well underway, and we expect topline results in the fourth quarter of 2020. We are further exploring the potential role of LIGHT as a driver of and biomarker for ARDS in additional studies...'"favipiravir / Generic mfg.MSN plans to roll out cheapest Covid-19 drug at Rs 33 per tablet (Deccan Herald) - Aug 13, 2020 - "...MSN Group has planned to launch the cheapest Covid-19 treatment drug - Favipiravir 200 mg, for Rs 33, according to multiple reports. The affordable version of the anti-viral drug will be marketed under the brand name 'Favilow'....The 400 mg version of Favilow will also be launched soon....'Favilow' will be available in 200 mg tablets....The company will be launching the drug on August 15..."An effective vaccine can help restore normalcy by end of 2021: Anthony Fauci (The Hindu Business Line) - Aug 16, 2020 - "'I do not think it is going to be 2024. I think it's going to be more like the end of 2021,' Fauci said in the interview. 'If you synergise and superimpose good, solid, careful, prudent public health measures with a vaccine that is effective - it doesn't have to be 100 per cent effective,' he said. 'If you get a vaccine into 2021, throughout the year, I believe, by the year 2021, the end of the year, we will be as good back to normal as we possibly can,' he added."Covid re-infection not confirmed, says WHO - Aug 14, 2020 - "Maria Van Kerkhove, technical lead on Covid-19 response at the WHO Health Emergencies Program, told a virtual press conference that some people could have PCR (polymerase chain reaction) positivity for many weeks, not just days, and it doesn’t necessarily mean that they are infectious for that long."EU reaches 1st deal to buy potential COVID-19 vaccine - Aug 15, 2020 - "The advance purchase agreement was reached after weeks of negotiations with AstraZeneca, according to Stella Kyriakides...Kyriakides had earlier said that the first vaccine against COVID-19 may be available towards the end of this year or early next year."
